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Learn how HER2 testing can help guide your treatment for breast cancer. Find out what HER2-positive, HER2-negative, and HER2-low mean and how they affect your prognosis and options.
HER2 is a member of the ERBB family of receptor tyrosine kinases that regulates cell growth and survival. Amplification or over-expression of the ERBB2 gene, which encodes HER2, is associated with some types of breast cancer and other tumors.
What is the life expectancy of a HER2-positive breast cancer patient? Life expectancy varies based on the cancer stage. On average, 90% of people with HER2-positive breast cancer are still alive 5 ...
Learn about HER2-positive breast cancer, a type of breast cancer that tests positive for a protein that promotes cancer cell growth. Find out how it is diagnosed, treated and prognosed, and why it is important to test every invasive breast cancer for HER2.
HER2 Overexpression in Human Cancer. Normal tissues have a low complement of HER2 membrane protein. Overexpression of HER2 is seen in 20% of breast and in some ovarian and gastric cancers, and it confers worse biological behavior and clinical aggressiveness in breast cancer (2, 21).Breast cancers can have up to 25-50 copies of the HER2 gene, and up to 40-100 fold increase in HER2 protein ...
Learn about HER2-positive breast cancer, a fast-growing form of invasive breast cancer that affects some people who have high levels of HER2 protein. Find out how it's diagnosed, treated and prevented, and what complications it may cause.
Learn about HER2 positive breast cancer, a type of cancer that grows more quickly and is more aggressive than other cancers. Find out how it is diagnosed, treated and researched at MD Anderson Cancer Center.
What does it mean to test HER2 status in breast cancer? After a breast cancer diagnosis, the oncologist may recommend testing the tumor for HER2 protein levels.HER2 plays a role in cancer cell growth, and high levels of this protein may indicate the presence of a fast-growing tumor likely to spread.Your care team may use medicines that target HER2 to fight tumors.
HER2 (human epidermal growth factor receptor 2) is a gene that can play a role in the development of breast cancer.
An early-stage HER2-positive (HER2+) breast cancer is always a shock, but today's treatment options should give you hope. Over the past 2 decades, advances in medicine have brought us new ...