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1adg
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1ADF, 1ADG PubMed Abstract: Thiazole-4-carboxamide adenine dinucleotide (TAD) is the active anabolite of the antitumor drug tiazofurin. Beta-methylene TAD (beta-TAD) is a phosphodiesterase-resistant analogue of TAD, active in tiazofurin-resistant cells. Beta-methylene SAD (beta-SAD) is the active selenium derivative of beta-TAD.
ALCOHOL DEHYDROGENASEBETA-METHYLENE-SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDEZINC ION
1adg: Crystallographic studies of two alcohol dehydrogenase-bound analogues of thiazole-4-carboxamide adenine dinucleotide (TAD), the active anabolite of the antitumor agent tiazofurin.
Page15 FullwwPDBX-rayStructureValidationReport 1ADG highlighted in the graph. For rings, the root-mean-square deviation (RMSD) between the ring inquestionandsimilarringsidentifiedbyMoguliscalculatedoverallringtorsionangles.
1ADG: CRYSTALLOGRAPHIC STUDIES OF TWO ALCOHOL DEHYDROGENASE-BOUND ANALOGS OF THIAZOLE-4-CARBOXAMIDE ADENINE DINUCLEOTIDE (TAD), THE ACTIVE ANABOLITE OF THE ANTITUMOR AGENT TIAZOFURIN
238,622 Structures from the PDB archive 1,068,577 Computed Structure Models (CSM) Display Files Download Files 1ADG | pdb_00001adg
1adg is a 1 chain structure with sequence from Equus caballus. It shows the binding of two analogues of TAD, the active anabolite of the antitumor agent tiazofurin, to the cofactor-binding cleft of alcohol dehydrogenase.
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PDB entry 1adg View 1adg on RCSB PDB site Description: crystallographic studies of two alcohol dehydrogenase-bound analogs of thiazole-4-carboxamide adenine dinucleotide (tad), the active anabolite of the antitumor agent tiazofurin Class: oxidoreductase (nad (a)-choh (d)) Keywords: oxidoreductase (nad (a)-choh (d)) Deposited on 1993-10-18, released 1994-01-31 The last revision prior to the ...
231,564 Structures from the PDB 1,068,577 Computed Structure Models (CSM) Structure Summary Structure Annotations Experiment