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HATU
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HATU (H exafluorophosphate A zabenzotriazole T etramethyl U ronium) is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid.
Aldrich-445460; HATU 0.97; CAS No.: 148893-10-1; Synonyms: 1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate; N ...
O- (7-azabenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate | C10H15F6N6OP | CID 6409673 - structure, chemical names, physical and chemical ...
HATU is a golden-standard reagent for generating an active ester from carboxylic acid and forming an amide bond without heating. It is a stable white powder, soluble in polar aprotic solvents, and performs well in the case of hindered substrates.
HATU was a third-generation coupling reagent with the ability to decrease racemization. HATU causes amine acylation or the formation of an amide bond.
HATU is a reagent used to generate an active ester from a carboxylic acid for peptide coupling. It can be used with Hünig's base to form amide bonds. See chemical structure, CAS number, purity, solubility, and references.
HATU is a reagent for alcohol and amine acylation reactions in peptide synthesis. It forms OAt-active esters with carboxylic acids and reacts with nucleophiles to afford acylated products.
HATU - chemical structure, common uses, and safety.Home Common Reagents HATU HATU Other Names: 1- [Bis (dimethylamino)methylene]-1H-1,2,3- triazolo [4,5-b]pyridinium 3-oxid hexafluorophosphate
HATU: A Highly Efficient, Stereospecific "Molecular Welder" in Peptide Chemistry 4/24/2025 2- (7-Azobenzotriazole)-N, N, N', N'-tetramethyluronium hexafluorophosphate (HATU, Fig. 1) is a highly efficient urea-nor-ionic peptide condensation reagent, which is superior in activity to the HOBt-based series of condensation reagents (HBTU, TBTU) due to the neighboring group effect of nitrogen atoms ...
HATU is a condensation reagent that activates carboxyl groups and promotes amide bond formation. It is widely used in organic and peptide synthesis, and has low toxicity and mutagenicity.