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KRT17
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KRT17 (Keratin 17) is a Protein Coding gene. Diseases associated with KRT17 include Steatocystoma Multiplex and Pachyonychia Congenita 2. Among its related pathways are Keratinization and Nervous system development. Gene Ontology (GO) annotations related to this gene include structural molecule activity and MHC class II receptor activity.
Keratin 17 is a protein encoded by the KRT17 gene in humans and mice. It is a type I cytokeratin found in epidermal appendages and involved in hair follicle development and cornification.
The KRT17 gene provides instructions for making a protein called keratin 17 or K17. Learn about this gene and related health conditions.
KRT17 Functions as a Tumor Promoter and Regulates Proliferation, Migration and Invasion in Pancreatic Cancer via mTOR/S6k1 Pathway
Gene target information for KRT17 - keratin 17 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
KRT17 is a multifunctional protein that regulates cell proliferation and growth and may promote tumor occurrence and development. This article analyzes the expression, mutation, prognosis, and molecular mechanisms of KRT17 in various tumors using databases and webservers.
Keratin 17 (KRT17; K17), a non-lamin intermediate filament protein, was recently found to occur in the nucleus. We report here on K17-dependent differences in nuclear morphology, chromatin organization, and cell proliferation.
Although new evidence from cells or animals suggests a relationship between Keratin 17 (KRT17) and cancer, no pan-cancer analysis is currently available. The expression level of KRT17 in generalized carcinoma was detected by the Tumor Immune ...
KRT17 is necessary for oncogenic transformation in Ewing sarcoma and accounts for much of the GLI1-mediated transformation function but via a mechanism independent of AKT signaling.
Overexpression of KRT17 is common in NSCLCs and indicates poor prognosis. Overexpression of KRT17 enhances the proliferation and invasiveness of NSCLC cells by activating the Wnt signaling pathway and EMT process. KRT17 is a potential indicator of NSCLC progression and poor survival.