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THP-1 is a human monocytic cell line derived from an acute monocytic leukemia patient. It is used to study monocyte-macrophage differentiation, macrophage physiology, and dendritic cell differentiation.
THP-1 is a suspension cell line derived from a patient with acute monocytic leukemia. It can differentiate into macrophages and dendritic cells and is used for cancer, immunology and toxicology research.
THP-1 is a human leukemia monocytic cell line, which has been extensively used to study monocyte/macrophage functions, mechanisms, signaling pathways, and nutrient and drug transport. This cell line has become a common model to estimate modulation of monocyte and macrophage activities. This review a …
THP-1 monocyte cell lines Engineered Human Reporter THP-1 Monocytes THP1 reporter cells are derived from THP-1, a human monocytic cell line. THP-1 cells were isolated from the peripheral blood of a male patient with acute monocytic leukemia.
Highlights • THP-1 cell line is a suitable in vitro cell model to study modulation of monocyte and macrophage functions. • The use of THP-1 cell line can help supporting the eventual in vivo proven bioactivities of food compounds and pharmacological activities of drugs. • THP-1 cell line can hint to potential responses that might occur in vivo, however, these should be validated by in ...
THP-1 is a human acute monocytic leukemia cell line derived from peripheral blood. It can differentiate into macrophage-like cells and has various genetic alterations, such as NRAS and TP53 mutations.
Explore THP-1 monocytes, vital in immunology and cancer research. 🌟 Learn about their isolation, differentiation, and applications in studying immune responses and inflammation.
THP-1 is a human leukemia cell line derived from a 1-year-old patient with acute monocytic leukemia. It can differentiate into macrophage-like cells and be polarized into M1 or M2 macrophages, making it a versatile tool for investigating monocyte and macrophage biology, functions, and interactions with cancer and immunotherapy.
Using the in vitro (THP-1 cells) and ex vivo (primary monocytes) approach side-by-side allowed us to make informed judgments on the usefulness of THP-1 cells as a model for primary monocytes. For example, monocytes, when compared with THP-1 cells, are far more responsive to LPS.
Learn how to culture, subculture, freeze and thaw THP-1 cells, a human monocytic leukemia cell line. Find out the basic information, characteristics, growth medium and tips for THP-1 cells.