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apiins
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Apiin is a natural flavonoid, a diglycoside of the flavone apigenin found in the winter-hardy plants parsley [1] and celery, [2] and in banana leaf. [3] The glycoside moiety at carbon-7 of apigenin, O-β-D-apiofuranosyl(→)2-β-D-glucosyl, is carried by several other flavones in parsley plant and seed. [4] The sugar apiose possibly play a role in winter hardiness of celery, duckweed and parsley.
The meaning of APIIN is a crystalline glycoside C26H28O14 obtained from parsley.
The docking scores reveal that many of the phytoconstituents display greater binding affinity than the reference compound (Table 15.1).The top eight compounds with the best binding affinity are listed in Table 15.2.Compared to Myricetin with a binding score of −5.4435 kcal/mol, the top listed compound shows a much higher binding affinity for the target protein.
Apiin, a major constituent of Apium graveolens leaves with anti-inflammatory properties. Apiin shows significant inhibitory activity on nitrite (NO) production (IC50 = 0.08 mg/mL) in-vitro and iNOS expression (IC50 = 0.049 mg/ mL) in LPS-activated J774.A1 cells. - Mechanism of Action & Protocol.
Foundation models for human vision tasks. Abstract. Meta Reality Labs present Sapiens, a family of models for four fundamental human-centric vision tasks - 2D pose estimation, body-part segmentation, depth estimation, and surface normal prediction.
Sapiens offers a comprehensive suite for human-centric vision tasks (e.g., 2D pose, part segmentation, depth, normal, etc.). The model family is pretrained on 300 million in-the-wild human images and shows excellent generalization to unconstrained conditions. These models are also designed for ...
#1 New York Times Bestseller • New York Times Readers' Pick: Top 100 Books of the 21 st Century • The Summer Reading Pick for President Barack Obama and Bill Gates. Official U.S. edition with full color illustrations throughout. From renowned historian Yuval Noah Harari comes a groundbreaking narrative of humanity's creation and evolution—a #1 international bestseller—that explores ...
Sapiens: A Brief History of Humankind (Hebrew: קיצור תולדות האנושות, Qitzur Toldot ha-Enoshut) is a book by Yuval Noah Harari, based on a series of lectures he taught at The Hebrew University of Jerusalem.It was first published in Hebrew in Israel in 2011, and in English in 2014. [1] [2] The book focuses on Homo sapiens, and surveys the history of humankind, starting from the ...
Professor Yuval Noah Harari is a historian, philosopher, and the bestselling author of Sapiens: A Brief History of Humankind, Homo Deus: A Brief History of Tomorrow, 21 Lessons for the 21st Century, and the series Sapiens: A Graphic History and Unstoppable Us. He is considered one of the world's most influential public intellectuals working today.
'Sapiens: A Brief History of Humankind' by Yuval Noah Harari is a bestselling non-fiction book, that takes us on a breath-taking ride through the entire history of our species - from our evolutionary roots to the age of capitalism and genetic engineering. Through its multidisciplinary, epic exploration of developments like the advent of agriculture, the creation of money, the spread of ...