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Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. [5] It may be used to prevent mother-to-child spread during birth or after a needlestick injury or other potential exposure. [5]
AZT, drug used to delay development of AIDS (acquired immunodeficiency syndrome) in patients infected with HIV (human immunodeficiency virus). AZT belongs to a group of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). In 1987 AZT became the first of these drugs to be approved by the U.S. Food and Drug Administration for the purpose of prolonging the lives of AIDS patients.
AZT, or azidothymidine, was originally developed in the 1960s by a U.S. researcher as way to thwart cancer; the compound was supposed to insert itself into the DNA of a cancer cell and mess with ...
AZT (Zidovudine) is an antiretroviral drug that inhibits HIV replication and is used in combination with other drugs. Learn about its indications, precautions, drug interactions, and how to prevent resistance.
Zidovudine (also known as AZT) is a medicine used to treat HIV infection and prevent transmission to babies. Learn about its description, dosage, precautions, side effects, and interactions with other medicines.
Zidovudine is an antiretroviral medication used for treating and preventing HIV infection. Learn about its side effects, dosage, interactions, pregnancy and breastfeeding safety, and more.
Zidovudine (Retrovir®, AZT) is a drug used for antiretroviral therapy (ART). It was first manufactured by GlaxoSmithKline. Glaxo's patent on zidovudine expired in 2005. Generic versions made by Aurobindo, Ranbaxy and Roxane were approved in 2005. Zidovudine is also known as azido-deoxythymidine, zidovudine or ZDV.
Introduction. Antiretroviral; HIV nucleoside reverse transcriptase inhibitor (NRTI). Uses for Zidovudine Treatment of HIV Infection. Used in conjunction with other antiretroviral agents for treatment of HIV-1 infection in adult and pediatric patients (>4 weeks of age).
Due to the pivotal role of AZT in HIV treatment, this review summarizes the most known effects -some of which are toxic side effects- induced by AZT a drug which is still used in the combined therapy of HIV-infected patients. Among the toxic side effects, a severe bone marrow toxicity manifested as anemia, neutropenia and siderosis, and caused ...
AZT belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors . Scientists funded by the NCI developed azidothymidine in 1964 as a potential treatment for cancer and while ...