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Enterovirus 71 (EV71) is a virus that causes severe neurological and hand, foot, and mouth diseases in children. Learn about its classification, replication, recombination, vaccine, and global epidemics from this Wikipedia article.
What it is First identified in the United States in 1969, enterovirus A71 (EV-A71) is one of more than 100 non-polio enteroviruses. Worldwide, EV-A71 is a common cause of hand, foot, and mouth disease (HFMD) in infants and young children. You are more likely to get infected with enteroviruses during summer and fall, but infections can happen year-round.
EV71 is considered to be the most severe neurotoxic enterovirus and severe EV71 disease has become a major public health problem in China. EV71 isolates can be clustered according to their genomic sequence into at least eight genogroups (A-H) but belong to one serotype.
Since the outbreak of the enterovirus 71 (EV71) infection in Malaysia in 1997, large epidemics of EV71 have occurred in the Asia-Pacific region. Many children and infants have died from serious neurological complications during these epidemics, and ...
Enterovirus 71 (EV71) is one of the major causative agents of outbreaks of hand, foot, and mouth disease or herpangina worldwide. This phase 3 trial was designed to evaluate the efficacy, safety, a...
Enterovirus 71 (EV71) has emerged as a major cause of neurological threat in the world following the eradication of poliovirus. Most EV71 infections commonly result in hand-foot-mouth disease or herpangina, and some cases are associated with brainstem encephalitis and acute flaccid paralysis. Mortal …
Enterovirus 71 (EV71) is a significant pathogen responsible for hand, foot, and mouth disease (HFMD), particularly affecting children. Its impact extends beyond mild symptoms, sometimes leading to severe neurological conditions like meningitis and encephalitis. The virus's prevalence in Asia has raised global public health concerns due to its potential for rapid transmission and serious ...
Enterovirus 71 Figure 1. The EV71 virion Discovered in 1969, human enterovirus 71 (EV71) is the causative agent of hand-foot-and-mouth disease (HFMD) in young children, with a subset of patients developing more severe neurological disease that can result in death.
What is Human Enterovirus 71 (EV71)? Human Enterovirus 71, often abbreviated as EV71, is a member of the Enterovirus genus within the Picornaviridae family [1]. EV71 is a positive-sense, single-stranded RNA virus [1]. It was first identified in California in 1969 and has since become a common cause of hand, foot, and mouth disease (HFMD), as well as other illnesses in children [1].
Virology EV71 shares a common morphology and structure with other members of the Picornaviridae family. The non‐enveloped, symmetrically icosahedral virion of about 30 nm in diameter, is one of the smallest viruses 90.