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Here, we report the first combined comprehensive analysis of the primary endpoints of the HD21 trial. METHODS. This international open-label phase III trial included adult patients aged ≤ 60 yrs with AS-cHL. Patients were randomized in a 1:1 ratio to PET2-guided 4-6 21-day cycles of either eBEACOPP or BrECADD. PET2 and PFS events were ...
The HD21 study is a Phase 3, multi-country, prospective, open-label, randomized, multicenter trial sponsored by the German Hodgkin Study Group (GHSG) with a PET-response adapted designed to assess the feasibility, efficacy, safety and tolerability of BrECADD, a novel, rationally designed, CD-30 intensified frontline regimen for patients with ...
The HD21 trial evaluated whether BrECADD could improve this risk-benefit balance over PET2-guided eBEACOPP, which is the standard of care in most European countries and is used in high-risk advanced-stage HL worldwide. 2,3. The transition from eBEACOPP to BrECADD adds brentuximab vedotin, omits bleomycin and vincristine, switches from ...
Re: AC HD21 dozers in reply to Jeremy Stoermer, 11-07-2001 18:42:57 Jeremy, There were 7 different series of Allis-Chalmers HD-21 crawlers from 1954 thru 1975.
By contrast, to be randomly assigned in this HD21 trial, patients had to be aged 18-60 years as eBEACOPP is not a standard of care in children or older patients. The corresponding 6-year progression-free survival rate for this age group in the ECHELON-1 trial was 84·4% ...
The Bosch HD21-2 2-speed hammer drill features a torque control auxiliary handle. This securely locks into place for maximum control in heavy duty drilling applications. It has a 2-speed gear box. This allows the user to match the speed to the application. This gives you either the power or precision necessary. 1/2 in. 3-Jaw Chuck for rugged ...
The HD21 brings the durability and hassle-free existence you've always wanted in a shiny new electric package. Starting at $1,799 . Additional fleet discounts available. / DURABILITY. Built from the same legendary cast deck as our gas-powered Heavy Duties, the HD21 excels when the going gets tough. With premium upgrades such as deck wear ...
1985 ALLIS-CHALMERS HD21 Crawler Dozers. USD $16,500 *Apply for Financing Opens in a new tab. Get Shipping Quotes Opens in a new tab. Location: Manchester, New Hampshire. Email Seller
Allis Chalmers HD21 Power: Engine: 225 hp 167.8 kW: Drawbar (tested) 135.12 hp 100.8 kW: Performance test details ... Mechanical: Drive: crawler Contracting band brakes: Open operator station. Photos: Allis Chalmers HD21 photos... Dimensions & Tracks: Weight: 45500 lbs 20638 kg: Tracks: Full dimensions and tracks ...