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IMP3 is a protein that binds to mRNA and plays a role in embryogenesis and cancer. It is a cytoplasmic stain that can help differentiate between reactive and malignant epithelial changes in various organs and is a negative prognostic factor for many tumors.
IMP3 is an RNA binding protein required for ribosomal RNA processing, which has been suggested to be a prognostic marker in a large variety of human types of cancer. However, available data on the prevalence of IMP3 expression are largely ...
IMP3 is a protein coding gene that encodes a component of the U3 small nucleolar ribonucleoprotein complex involved in ribosomal RNA processing. It is located on chromosome 15 and has aliases such as BRMS2, MRPS4 and C15orf12.
IMP3 is a protein encoded by the IMP3 gene in humans and mice. It is involved in ribosome biogenesis and rRNA processing, and interacts with the U3 snoRNP complex.
IMP3 recognizes an array of distinct sequence elements To dissect the complex RNA-binding properties of IMP3, we used individual, GST-tagged subdomains and applied an in vitro SELEX procedure ...
IMP3 is an oncofetal protein overexpressed in thyroid cancers. It shows potential as a biomarker and target for therapy, aiding diagnosis and treatment response.
IMP3 forms a ternary complex with IMP4 (612981) and MPP10 (MPHOSPH10; 605503) that interacts with U3 small nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing (Granneman et al., 2003).
RNA-binding protein IMP3 is a novel regulator of MEK1/ERK signaling pathway in the progression of colorectal Cancer through the stabilization of MEKK1 mRNA. Correlations of expressions of IMP3 and VEGF with stage of osteosarcoma, microvascular density and pulmonary metastasis.
Learn about the IMP3 gene, its function, regulation, and role in various diseases. Explore the latest research on IMP3 and its potential clinical applications.
IMP3, a member of insulin-like growth factor II m RNA binding protein family, seems to be promising in the diagnosis of carcinomas of many organs as well as malignant melanomas and some sarcomas. It is postulated that it might be a marker of ...