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The LASTE trial was a multicenter, prospective, open-label, randomized, controlled trial with blinded outcome evaluation. 9 The trial protocol (available with the full text of this article at NEJM ...
The LASTE trial was terminated early after several interim studies showed benefit associated with thrombectomy in acute ischemic stroke with large infarct size. The current data similarly demonstrate sizable improvement in post-infarct disability, an effect which persisted to at least 6 months. All-cause death, which occurred in over half of ...
To the Editor: Costalat et al. (May 9 issue)1 report positive outcomes in the Large Stroke Therapy Evaluation (LASTE) trial, which investigated endovascular thrombectomy for unrestrictedly large st...
Define Laste. Laste synonyms, Laste pronunciation, Laste translation, English dictionary definition of Laste. imp. 1. imp. of Last, to endure. Webster's Revised Unabridged Dictionary, published 1913 by G. & C. Merriam Co
The LASTE Trial. LASTE, conducted in 24 high-volume stroke centers experienced in thrombectomy in France and six in Spain, included 324 patients (median age 74 years; 52% men) who presented within 6.5 hours after symptom onset with a proximal cerebral vessel occlusion in the anterior circulation and a large infarct defined by an ASPECTS of 5 or ...
laste (imperative last, present tense laster, passive lastes, simple past and past participle lasta or lastet, present participle lastende) (transport) to load laste om - to transship to load (data, a file) laste ned - to download; to blame; Antonyms [edit] losse; Derived terms [edit] fullastet, fullasta; lasting;
LASTE trials, we aimed to perform an updated system-atic review and aggregate meta-analysis to better eval-uate the overall efficacy and safety of EVT for patients with AIS-LVO with large infarct core. We further sought to evaluate the benefits and risks of EVT in impor-
Methods and design: LArge Stroke Therapy Evaluation (LASTE) is an international, multicenter, Prospectively Randomized into two parallel (1:1) arms, Open-label, with Blinded Endpoint (PROBE design) trial. Eligibility criteria are diagnosis of AIS within 6.5 h of last-seen-well (or negative fluid-attenuated inversion recovery (FLAIR) if unknown ...
LArge Stroke Therapy Evaluation - LASTE. OBJECTIVES To determine the efficacy and safety of mechanical thrombectomy plus best medical treatment compared to best medical treatment alone in patients with large acute ischemic stroke with ASPECTS 0-5 and large vessel occlusion of the anterior circulation.
The LASTE protocol "Large Stroke Therapy Evaluation" aims to study the efficacy and safety of mechanical thrombectomy in the acute phase of cerebral infarction less than 7 hours for patients with a large volume of necrosis defined by a score ASPECT from 0 to 5. The patients will be followed 6 months after the stroke.