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linc00152
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LINC00152-005: 1096: No protein- lincRNA-A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt.
A comprehensive sequence analysis of LINC00152 revealed a highly similar paralog annotated as MIR4435-2HG and several splice variants of both transcripts. The shortest and most abundant isoform ...
Long non-coding RNA LINC00152 (cytoskeleton regulator, or LINC00152) is an 828-bp lncRNA located on chromosome 2p11.2. LINC00152 was originally discovered during research on hepatocarcinogenesis and has since been regarded as a crucial oncogene that ...
Meanwhile, linc00152 was involved in cancer-related pathways, infection and immune response-associated pathways by enriched analysis using TCGA data. Finally, linc00152 was confirmed to promote the proliferation, migration and invasion in MDA-MB-231, SGC-7901 and 786-O. Moreover, RIP and RNA pull-down assays indicated that linc00152 can bind to ...
LINC00152 is regulated by multiple transcription factors and DNA hypomethylation. In addition, LINC00152 participates in the regulation of complex molecular signaling networks through epigenetic regulation, protein interactions, and competitive endogenous RNA (ceRNA).
LINC00152 has been associated with poor prognosis of non-small cell lung cancer (NSCLC) patients. It has been shown to be highly expressed in tumor tissues and peripheral blood samples of NSCLC patients through analysis of the data from quantitative real-time polymerase chain reaction (qRT-PCR) assay, RNA sequencing (RNA-seq), The Cancer Genome ...
Long intergenic non-coding RNA 152 (LINC00152) is a recently identified tumor-promoting long non-coding RNA. However, the biological functions of LINC00152 in colorectal cancer (CRC) remain ...
Long non-coding RNA LINC00152 (cytoskeleton regulator, or LINC00152) is an 828-bp lncRNA located on chromosome 2p11.2. LINC00152 was originally discovered during research on hepatocarcinogenesis and has since been regarded as a crucial oncogene that regulates gene expression in many cancer types. LI …
Underlying regulatory mechanisms of LINC00152 in human cancers. (A) LINC00152 may interact with THBS1 mediated by miR‐18a‐5p. (B) LINC00152 may act as a competing endogenous RNA (ceRNA) to regulate the expression of miR‐193a‐3p, and then regulate ERBB4. (C) LINC00152 can activate the mechanistic target of rapamycin (mTOR) pathway by binding to the promoter of EpCAM.
LINC00152 expression levels were detected through RT-PCR. For tumor engraftment, HGC-27 cells that receive … This study aimed to annotate the role of long intergenic non-coding RNA 152 (LINC00152) in CD8+ T cells mediated immune responses in gastric cancer (GC) and the underlying mechanism.