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Type 2 diabetes - Symptoms and causes - Mayo Clinic

Learn about type 2 diabetes, a condition that affects how the body uses insulin and sugar. Find out the risk factors, symptoms, diagnosis and treatment options for this chronic disease.

Type 2 Diabetes - StatPearls - NCBI Bookshelf

T2DM is an insulin-resistance condition with associated beta-cell dysfunction. Initially, there is a compensatory increase in insulin secretion, which maintains glucose levels in the normal range. As the disease progresses, beta cells change, and insulin secretion is unable to maintain glucose homeostasis, producing hyperglycemia.

Pathophysiology of Type 2 Diabetes Mellitus - PMC

Abstract Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin. Because insulin release and activity are essential processes for glucose homeostasis, the molecular mechanisms involved in ...

Type 2 Diabetes Mellitus - Harvard Health

What Is It? Type 2 diabetes is a chronic disease. It is characterized by high levels of sugar in the blood. Type 2 diabetes is also called type 2 diabetes mellitus and adult-onset diabetes.

Type 2 diabetes - Wikipedia

Type 2 diabetes is a form of diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. It is largely preventable by staying at a normal weight, exercising regularly, and eating a healthy diet. It can cause serious complications such as heart disease, stroke, blindness, kidney failure, and amputations.

Type 2 Diabetes - NIDDK

Learn about type 2 diabetes, a disease that affects how your body uses glucose, from the National Institute of Diabetes and Digestive and Kidney Diseases. Find out the risk factors, diagnosis, management, complications, and prevention of type 2 diabetes.

Understanding Type 2 Diabetes | ADA

Learn about type 2 diabetes, a condition where your body does not use insulin properly. Find out the common symptoms, how to prevent complications, and how to take a risk test on the American Diabetes Association website.

Type 2 diabetes mellitus in adults: pathogenesis, prevention and ...

Type 2 diabetes (T2D) is a disease characterized by heterogeneously progressive loss of islet β cell insulin secretion usually occurring after the presence of insulin resistance (IR) and it is ...

Type 2 Diabetes | Diabetes | CDC

Overview More than 38 million Americans have diabetes (about 1 in 10), and about 90% to 95% of them have type 2 diabetes. Type 2 diabetes most often develops in people 45 or older, but more and more children, teens, and young adults are also developing it.

NIDDM (Non-Insulin Dependent Diabetes Mellitus) - T2DM

Non-insulin-dependent diabetes mellitus (NIDDM) also known as type 2 diabetes mellitus (T2DM), is a chronic illness in which the body does not use insulin properly. Unlike type 1, type 2 diabetes often does not develop in children, it is most common among older adults (people in their 40's or 50's). However, it can affect children and adolescents that have childhood obesity. T2DM is ...

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