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The T78V substitution (Figure 2C) does not change the number of buried water molecules on the side proximal to Met80, but introduces an additional water molecule (Wat168) on the side proximal to His18. The distance between Wat166 and the ferric heme iron is shortened as well but not as much as in T49V/K79G. As a consequence of the T78V ...
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T78V/K79G, the loss of hydrogen bonds from Thr78 upon the T78V substitution is compensated by new interactions HP6 forms with Thr49. The change in the stability of the ferrous species upon the ...
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Download scientific diagram | Spectra of ferric K79G (black), T49V/K79G (red), and T78V/K79G (blue) at pH 4.5. (A) Electronic absorption spectra of ferric proteins at 22 ± 2 °C. The inset is the ...
Standard Gun Using Shell Type 2 (240 Damage): Theoretical Damage Per Minute Nominal DPM: 1735.2 50% Crew: 1401.6 75% Crew: 1603.2 100% Crew: 1809.6 100% Crew Vents: 1850.4 Rammer: 2011.2 Both: 2056.8 Both and BiA: 2102.4 Both and Max Crew %: 2193.6 Advantageous Damage Per Minute
M18BP1S77A-T78V-S93A astherepresentativePLK1 loss-of-binding mutant, we examined HJURP recruitment using the same strategy as above. ExpressingM18BP1S77A-T78V-S93A incellsresulted in an almost complete loss of HJURP from centromeres(Fig. 2,C andD, and fig.S10).We conclude that, during early G
The polypeptide ensemble of T78V/K79G in the pH range from 3.5 to 6.0 is comprised of conformers with a degree of α-helical structure and an average Trp to heme distance very similar to that in ...
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Reliability. Its 90 mm gun is a real threat, combining good damage with nice accuracy and high stabilisation. Speed. The T78 gets anywhere quickly, thanks to its great acceleration and top speed