为您找到"
zfy
"相关结果约100,000,000个
ZFY is a protein coding gene on the Y chromosome that encodes a zinc finger protein. It is involved in male sex determination and has been associated with some disorders and diseases.
ZFY is a gene that encodes a zinc finger protein involved in transcription and meiotic sex chromosome inactivation. It is located on the Y chromosome and has two splice variants in humans and two paralogs in mice.
Alternating zinc fingers in the human male associated protein ZFY: 2D NMR structure of an even finger and implications for "jumping-linker" DNA recognition.
ZFY is a gene on the Y chromosome that encodes a protein with multiple 'finger' domains. It is involved in sperm or testis maturation and has a conserved sequence with ZFX on the X chromosome.
Gene target information for ZFY - zinc finger protein Y-linked (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.
Functional Associations. ZFY has 2,379 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 79 datasets.
ZFY encodes a zinc finger protein that may regulate gene expression. It is involved in some rare disorders such as campomelic dysplasia and Frasier syndrome.
INTRODUCTION. In eutherian (placental) mammals, ZFY genes appear to play an important role in male development, as they have been found on the Y chromosome in many species including humans and mice (). ZFY genes have a widely expressed X-linked homologue, ZFX, that codes a highly similar protein; this has been shown to be a regulator of self-renewal in embryonic and haematopoeitic stem cells ().
ZFY is a candidate for the primary sex-determining gene (TDF, testis-determining factor) on the human Y chromosome. We have isolated cDNA clones of ZFY and its homologue on the X chromosome, ZFX. The transcripts of these genes are very similar to each ...
Reading time: 2 minutes A five-year study at the University of Hawaiʻi 's medical school will investigate how a key gene, called Zfy, impacts sperm production and fertility. Funded by a $2.4 million grant from the National Institutes of Health, the research aims to uncover new insights into male reproduction and tackle infertility challenges.