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ZFY is a gene that encodes a zinc finger protein involved in transcription and meiotic sex chromosome inactivation. It is located on the Y chromosome and expressed in various tissues, especially testis and prostate.
Complete information for ZFY gene (Protein Coding), Zinc Finger Protein Y-Linked, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
In 1987, the geneticist David Page and his associates 2 identified the first coding gene on the human Y, called ZFY.The gene looked like a winning candidate: it was in the right place; it was ...
The Y-linked zinc finger gene ZFY is conserved across eutherians and is known to be a critical fertility factor in some species. The initial studies of the mouse homologues, Zfy1 and Zfy2, were performed using mice with spontaneous Y chromosome mutations and Zfy transgenes. These studies revealed that Zfy is involved in multiple processes during spermatogenesis, including removal of germ cells ...
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Background. The Y chromosome encoded zinc finger protein gene, Zfy, has once been in the center of attention as a potential candidate for a testis-determining factor [].When the attention went to another Y chromosome gene, Sry [], Zfy was quickly forgotten, and it has taken more than two decades for it to re-emerge with newly ascribed spermiogenic roles.
ZFY is a zinc finger gene on the Y chromosome that was once thought to be the testis-determining factor (TDF) in humans. This review summarizes the structure, expression and function of ZFY and its relatives in mice and other mammals.
Alternating zinc fingers in the human male associated protein ZFY: 2D NMR structure of an even finger and implications for "jumping-linker" DNA recognition.
ZFY (ZNF911) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies.