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NCBI Finder
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ORF finder searches for open reading frames (ORFs) in the DNA sequence you enter and returns the range and protein translation of each ORF. You can use ORF finder to search newly sequenced DNA for potential protein encoding segments, verify predicted proteins with SMARTBLAST or BLASTP.
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The Basic Local Alignment Search Tool (BLAST) finds regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches. BLAST can be used to infer functional and evolutionary relationships between sequences as well as help identify members of gene families.
NCBI Antimicrobial Resistance Gene Finder (AMRFinderPlus) This software and the accompanying database are designed to find acquired antimicrobial resistance genes and point mutations in protein and/or assembled nucleotide sequences. We have also added "plus" stress, heat, ...
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NCBI has developed AMRFinderPlus, a tool that identifies AMR genes, resistance-associated point mutations, and select other classes of genes using protein annotations and/or assembled nucleotide sequence. AMRFinderPlus is used in the Pathogen Detection pipeline, and these data are displayed in NCBI's Isolate Browser.
NEBcutter - On-line DNA restriction mapper tool. This tool will take a DNA sequence and find the large, non-overlapping open reading frames using the E.coli genetic code and the sites for all Type II and commercially available Type III restriction enzymes that cut the sequence just once.
If you've ever tried searching for a genomic location in NCBI's Genome Data Viewer (GDV) or Variation Viewer and found that your search term didn't work, it's time to try again! We recently expanded support for searches in our genome browsers using non-NCBI identifiers such as HGVS patterns (e.g. NM_001318787.2:c.2258G>A) and Ensembl IDs. You can also search by chromosome coordinates ...