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Introduction Q-TOF-MS is an analytical technique that advantageously combines the benefits of two different mass analysers. Utilising the high compound fragmentation efficiency of quadrupole technology in combination with the rapid analysis speed and high mass resolution capability of time-of-flight, a unique 'hybrid' analyser was introduced. 1 Originally developed in the early 1980s, the ...
Bruker offers a range of QTOF instruments for high-resolution, high mass accuracy analysis of all ions simultaneously. QTOF MS is used for various applications, such as proteomics, metabolomics, contaminants screening, and structural proteomics.
Industry-leading full scan, accurate mass QTOF technology. Choose from space-saving benchtop mass specs for routine, high throughput and resolution workflows to Triple TOF instruments for more complex quantitative and qualitative analyses.
The Revident LC/Q-TOF embodies the next generation of quadrupole time-of-flight instruments featuring truly innovative (electronic) instrument architecture together with instrument intelligence, a novel, ultrafast detector, and an updated, robust calibrant delivery system. Excelling in routine screening, high resolution, accurate-mass quantitation, identification of unknowns, and high ...
Abstract Gas chromatography/ quadrupole time-of-flight mass spectrometry (GC/Q-TOF) offers high mass resolution and accurate mass data with the ability to perform structure elucidation and confirmation via MS/MS processes for a myriad of analytes in environmental and biological matrices. The ability of GC/Q-TOF to accurately measure persistent organic pollutants and deconvolve the data to ...
Q-TOF mass spectrometry is a type of mass spectrometry that combines a quadrupole mass analyzer with a time-of-flight (TOF) analyzer. It offers high sensitivity, resolution, and mass accuracy, making it a powerful tool for metabolomics research.
What is Q-TOF? Q-TOF (Quadrupole Time-of-Flight) is a type of mass spectrometer that combines a quadrupole mass analyzer with a time-of-flight (TOF) mass analyzer. This combination provides high resolution, accurate mass measurement, and high sensitivity, making it useful for identifying and quantifying compounds in complex samples. It is commonly used in proteomics, metabolomics, and drug ...
Q-TOF mass spectrometers combine TOF and quadrupole instruments, a pairing that results in high mass accuracy for precursor and product ions, strong quantitation capability, and fragmentation experiment applicability. The Q-TOF MS uses a quadrupole (four parallel rods arranged in a square formation), a collision cell, and a time of flight unit to produce spectra. Lighter ions accelerate faster ...
A brief introduction is presented to the basic principles and application of a quadrupole-time-of-flight (TOF) tandem mass spectrometer. The main features of reflecting TOF instruments with orthogona...
The Q-TOF GC-MS autotune routine automatically sets the detector gain and Amp Offset parameters to satisfy these conditions. The advantage of the ADC acquisition system relative to the TDC acquisition system (discussed in the next section) becomes apparent when multiple ions of a given mass arrive at the detector within a single transient.